Research

OVERVIEW

The rich array of research encompassed by CBIS includes basic science, translational, and clinical projects designed to address challenges and capitalize on opportunities in biomedical imaging science, education, and patient care. By bringing together communities throughout the University, CBIS has constructed a vast network of applied biomedical imaging research. This matrix includes new configurations of scientific teams at the interstices of disciplines as well as research projects on scales ranging from angstroms to centimeters.

CBIS-affiliated programs and centers offer an incredible breadth and depth of applied biomedical imaging investigation, exploiting new bioscience knowledge to unveil disease pathways and to create innovative treatment strategies in areas such as the following:

• the development of molecular imaging assays for studying biological systems to provide breakthroughs in the early detection and treatment of disease;
• the use of imaging to explore functional and clinical genomics as well as the sequencing and the genetic basis of disease to improve diagnosis and therapy;
• the study of neuronal function and neurological disease through imaging as well as the creation of new imaging diagnostic tools and therapies for patients with cognitive disorders;
• the employment of imaging techniques in the evaluation of neuroprotectants for ischemic strokes and in the stenting of carotid and vertebral arterial stenosis;
• the translation of basic science discoveries in advanced MRI techniques to create new hope for those who suffer from acute stroke, vascular malformations, and aneurysms; and
• the use of multimodality molecular imaging strategies to study oncogenes and tumor suppressor genes; cell cycle regulation; cancer genomics; and cancer stem cells, as well as to connect preclinical models of cancer with the clinical management of cancer.

CBIS research also includes projects in data and image analysis, interpretation, and modeling such as developing computational models to analyze molecular pathways in disease initiation and progression; increasing the information acquired from diagnostic imaging modalities; creating computer-aided detection systems; developing algorithmic and mathematical tools for data analysis; and creating a HIPAA-compliant biomedical data repository based on emerging informatics standards. Biodesign, biophysics, and bioengineering of imaging technology are also important components of CBIS. Many of our scientists advance the design and formation of imaging technology by developing cutting-edge techniques and tools in areas such as digital X-ray imaging, pulse sequence design, and hybrid imaging systems.

The research described above and the research links below include just a few of the myriad of biomedical imaging projects accessible through CBIS.